THIS is what SUGAR Does to Your Immune System (Plot Twist!)

THIS is what SUGAR Does to Your Immune System (Plot Twist!)

THIS is what SUGAR Does to Your Immune System (Plot Twist!)

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THIS is what SUGAR Does to Your Immune System (Plot Twist!)

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THIS is what SUGAR Does to Your Immune System (Plot Twist!) – Thomas DeLauer

A meta analysis, published in The American Journal of Clinical Nutrition looked at 83 research studies and concluded that a diet rich in fruits and vegetables actually improves immune function – conversely, a diet rich in processed foods and man-made sugars can suppress the immune system

HOWEVER, sugar may or may not act as an immunosuppressant, depending on different conditions in the body…

For a rule of thumb, excessive sugar consumption depletes the body’s nutrient balance, which triggers inflammation

Study – The American Journal of Clinical Nutrition

According to a 1973 study done by Loma Linda University, published in The American Journal of Clinical Nutrition, when you eat 100 grams of sugar, your white blood cells are 40% less effective at killing germs

Expanding Further

We don’t really feed or starve bacteria in the traditional sense, but consume or don’t consume food to combat the inflammation depending on the type of illness

Essentially, you want to starve a bacterial infection and feed a viral one

Additional

A study published in the The Journal of Clinical Investigation entitled, “Sugar makes neutrophils RAGE: linking diabetes-associated hyperglycemia to thrombocytosis and platelet reactivity” found that high blood glucose levels trigger neutrophil release of S100 calcium-binding protein A8/A9 (S100A8/A9), which binds to the receptor for advanced glycation end products (RAGE) on Kupffer cells, ultimately leading to increased thrombopoietin (TPO) production in the liver.
TPO causes megakaryocyte proliferation and increased platelet production.

Supplementation with glucose blocks ketogenesis – Bacterial sepsis is inducing reactive oxygen species-mediated cytotoxicity.

Ketones are able to stimulate potent FOXO transcription factors leading to the expression of endogenous antioxidants and mitigate the damage. Glucose inhibits ketogenesis and prevents the protective effect.

The mechanism of viral infection is different. Unlike bacteria, the injects its genetic material inside the infected cell and induces Endoplasmic Reticulum Stress.

Here, the blockage of glucose further worsens the ER stress and leads to tissue dysfunction. They further investigated the effect of ketones by creating mice deficient in PPAR which stimulates ketogenesis.

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