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people will simply say that when you’re in ketosis you’re burning fat for fuel okay that’s an overgeneralization but to some degree is true we are utilizing fats but I want to give you a really clear breakdown between what fat burning is fatty acid oxidation and what creating ketones are and burning ketones for fuel okay they’re slightly different but when you’re in ketosis you can utilize both so you’re gonna get basically a fat loss crash-course okay so let’s go ahead and break it all down and we give you a really cool analogy so just when this video starts to get a little complex I’m gonna bring it back down to earth with an epic analogy that’s gonna change the way you look at fat metabolism forever hey we have new videos almost every single day at 7:30 a.m. Pacific time so please I ask you to hit that red subscribe button so you don’t miss out and then also hit that Bell icon so you can turn on notifications I also want you to check out boo foods okay these guys are great I met them when I was at keto Con in Austin Texas and what attracted me to them is the fact that they have created keto treats that are legitimately clean okay they’ve made these keto bites that are now available at Whole Foods so you can go to Whole Foods and check them out there’s awesome little keto treats that are sweetened with organic monk fruits so no sugar alcohols at all and then they’re put together with pea protein just really good sustainable ingredients so super-clean keto snack they also have some cookie dough they have some amazing stuff but the keto bites are something that honestly you can munch on all the time they’re not gonna blow to you they’re not gonna give you that upset stomach and the cool thing is you can get them down at the link below or you can check them out at Whole Foods so big thank you to boo foods or making this video possible and for making keto tasty again alright let’s go ahead and talk about what fat burning is okay so fat is stored in what’s called adipocytes okay we have or adipocytes depending on if you’re a potato potato kind of guy basically we have little cells within our body that is our adipose tissue it’s our fat tissue and fatty acids live inside those little pockets that’s why if you were to kind of squeeze your belly fat you can almost feel little pods right like little seeds those are the cells in which fatty acids live in and they get bigger and they get smaller so what ends up happening is when we start the process of fatty acid oxidation or fat burning the fat is liberated from its little house and it goes into the bloodstream and then it reaches the cell that needs it most of the time it’s a muscle cell once it hits the cell it goes to the mitochondria which is a word we hear all the time nowadays right the mitochondria the energy powerhouse of the cell what happens is the fatty acid that left the fat cell now goes through the mitochondrial membrane and into what’s called the mitochondrial matrix this mitochondrial matrix is where fat burning really occurs okay this is where beta oxidation or fatty acid oxidation occurs now we break it down into step two this is where things get a little bit more complicated but again it’ll all make sense just stick with me I promise okay beta oxidation or fatty acid oxidation is a now occurring when carbon molecules are getting chopped off of the fatty acid chain so a fatty acid chain can be a number of carbon molecules like for example MCTS are gonna be eight carbon chains right so in the process of fatty acid oxidation chunks are getting chopped off okay so two carbon acetyl coenzyme a molecules are chopped off at a time so in the case of MCT oil it’s eight carbon chain so two chopped four chopped six chopped eight chopped okay and this progressively happens until the fatty acid chain is all gone just like that right okay now as a by-product we have something called nadh and fadh2 the electron transport chain I’ll talk about that in a second but through this process we’re liberating one acetyl coenzyme a and we’re liberating nadh and fadh2 long in the short of it is basically we have an ax that’s chopping up the fatty acid chain into a different energy molecule okay then this step 3 that acetyl coenzyme a that we liberated from the chopping process goes into the Krebs cycle remember the Krebs cycle from biology classes just simply where we create energy now when it goes through the Krebs cycle it gets converted into co2 okay it’s a perfect indicator when it gets converted into co2 that’s how we know we’re burning fat it’s the end of the process so when you working out when you’re pushing it and you’re exhaling a lot because you’re breathing a lot it’s an indicator that you’re burning more fat every time you exhale you’re expelling co2 which is a byproduct of the Krebs cycle whether it’s fat or carbohydrate metabolism now when you start having that respiratory rate increase because you’re working out that’s more fatty acid oxidation that’s more just Krebs cycle that’s going on because you’re moving faster now the Krebs cycle is the same whether it’s going to be for fats whether it’s going to be for proteins carbs ketones okay it’s the end of the line ultimately where we create energy okay now the nadh and fadh2 on placated all that does is contribute to what’s called the electron transport chain which creates a tendancy triphosphate creates energy let’s not really worry about that right now so what is the difference between fat burning and fat oxidation quite honestly they’re kind of the same fat burning is more so a colloquialism so it’s just a simplification of kind of a just a non-scientific term right well we could break it down a little bit more I think fat burning talks to the whole process liberating fats from the tissue putting them into the bloodstream going into the cell going into the mitochondria the chopping process the whole beta-oxidation process then of course the Krebs cycle that’s the whole process of fat burning I feel like fatty acid oxidation is more so limited to just like what’s going on in the mitochondrial matrix so fat burning is a generalization for all of this happening now here’s a really cool analogy it’s gonna make it all make sense let’s look at fat burning or fat oxidation in the sense of a forest all the way down to a campfire your fat cells the fat throughout your body is your forest you have a forest of logs the potential logs a forest what happens is the next phase the fatty acids that are broken down from the stored form of fats are big logs so the forest has been chopped down but now you’ve got big logs that are going on a tractor trailer okay that is your fatty acid okay the logs then the logs get delivered to the campsite okay there are basically logs going to the campsite to the campfire this campfire is the mitochondria the muscle cell it’s the site at which energy is going to be made so that logs are now getting delivered okay next up we have beta oxidation that is the ax okay the beta oxidation is the process of taking these logs and chopping them into smaller logs the smaller logs that it gets chopped into is gonna be acetyl coenzyme a the byproduct of beta oxidation so now we’ve taken logs through beta oxidation the X we have now chopped the logs into acetyl coenzyme a that acetyl coenzyme a is now firewood which now gets thrown on to the fire which is the Krebs cycle creating energy so it’s now burning and we now have energy now for those of you that are science nerds the nadh and the fadh2 i was talking about think of those as little scraps of wood that were a byproduct of the chopping that you can throw on the fire to get a little like sizzle little spark a little extra energy okay now I promised you I would explain the difference between ketone generation this is where things get really interesting because ketones and how they create energy are slightly different than how we just take direct fat for energy okay ketones create energy in a different way we still have the forest of fat I want shirt that says that the forest of fat okay we still have the logging process the trees are still chopped down and they’re chopped down into fatty acids but here’s where it’s different instead of the logs getting driven to the camp site the logs get driven to the liver and the liver ends up acting as the axe ketogenesis takes those fatty acids and turns them into ketones okay and those ketones go to a different place those ketones go to I want you to think of it like this instead of a camp site let’s think of a fireplace okay in order to get firewood into your home to put into the fireplace it needs to be in pretty small chunks you can’t deliver a big log to in through your front door like you could deliver a log to a campground so what happens is you require the liver the axe ketogenesis to chop the logs into small pieces so that you can get them into your house the blood-brain barrier is like the front door of your house right so it’s like an order for ketones to get into your brain they have to be small enough to be able to fit through the front door so normal fats don’t affect the brain they don’t get into the brain whereas ketones do because they’re chopped up small enough by the axe the lumberjack the liver you see it all makes sense so ketones are a different world do we still liberate fat first yes so for those people out there that say hey you’re marketing gimmicks by saying fat for fuel is a total joke it’s not a total joke the first part is absolutely true and it just does something different and the cool thing is is when you’re in ketosis and you have both occurring you create ketones but your muscle cells still go through beta oxidation – you don’t just strictly go through ketogenesis ketogenesis occurs for the ketones that are needed for different cells and fatty acids are still utilized by the muscle cell so now you know how this works no more saying that fat metabolism isn’t cool because honestly we just made it cool so at the end of it all we have to give credit where credit’s due okay fatty acid metabolism and keto metabolism are two very distinct things that are very powerful within the body but it all comes down to burning fat as always keep it locked in here on my channel and I’ll see you in the next video
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This is How Your Body Uses Fat – Fun Analogy
Fat Burning is NOT Fat Oxidation – How Your Body Burns Fat – Thomas DeLauer
Fat is stored in fat cells called adipocytes. When energy is needed, fat is released from adipocytes into the bloodstream and travels to the cells that need it, such as a skeletal muscle cell. Once inside said skeletal muscle cell, the fatty acid is transported across the mitochondrial membrane into the inner mitochondrial matrix. Here it undergoes β-oxidation.
β-oxidation is a cyclical process in which 2-carbon acetyl-CoA molecules are progressively chopped off the end of a fatty acid chain until the entire fatty acid chain has been decomposed into acetyl-CoA. Each cycle of β-oxidation liberates one acetyl-CoA and two electron carriers (NADH and FADH2).
Acetyl-CoA then goes into the central metabolic pathway called the Kreb’s cycle to be fully oxidized/converted into CO2 and, in the process, generates more NADH and FADH2 (i.e. proteins, carbs, and ketones are all also converted into acetyl-CoA to go into the Kreb’s cycle). In the end, NADH and FADH2 provide the electrons to produce ATP via the electron transport chain.
A colloquialism (non-scientific term) used to refer to the conversation of fat tissue into energy.
Also known as β-oxidation (or β-oxidation plus the Kreb’s cycle), this scientific term refers to the biochemical processes that happen within mitochondria in which longer fatty acid chains are broken down to create energy.
Relationship between “Fat Burning” and “Fat Oxidation”:
It’s fair to say that “fat burning” refers to the whole process of fat in fat tissue being turned into energy, whereas “fat oxidation” refers either directly to (i) β-oxidation or to (ii) β-oxidation plus the oxidation of acetyl-CoA into CO2 (your choice). (i) is specific to fat. (ii) is more accurate, but confuses the issue slightly because all macronutrients are converted into acetyl-CoA. In brief, “fat oxidation” is a component of “fat burning,” the latter of which I also take to include the liberation of fat from adipocytes and its transport to other cells.
The “Log” Analogy!
Fat Cells: The Forest
Fatty Acid: Chopped-Down Tree/Long Logs
Muscle Cell Mitochondria: Campsite
Kreb’s cycle: Fire
Your fat cells are like a forest. To access the fire fuel, you first need to chop down the tree and transport the long wooden logs (fatty acids) to your campsite where you want to light the fire. Once at your campsite (muscle cell mitochondria), you can take your axe (β-oxidation) and chop up the long wooden logs (fatty acids) into smaller bits of firewood (Acetyl-CoA), which can then go on the fire (Kreb’s cycle).
The “Log” Analogy, (adapted to include ketones)!
β-oxidation Ketogenesis: Axe/lumberjack
Acetyl-CoA Ketones: Firewood
Brain: The Fireplace
Blood-brain barrier: The Front Door of Your House
Now imagine you want to light a fire in the fireplace in your house (your brain). You can’t very well take a whole chopped-down tree or long logs and move them through your front door (blood-brain barrier). Instead, you first need to chop up and process the long logs (fatty acids) into smaller bits of firewood and then transport those into your house. This chopping up and processing happens by the axe/lumberjack in your liver (ketogenesis), the smaller bits of brain-accessible firewood being ketones!
Beta Oxidation pathways follow a circadian rhythm. Study from PLOS One found that “mitochondrial fatty acid β-oxidation enzymes, i.e. carnitine palmitoyltransferase-1α (Cpt-1α) and medium chain acyl-CoA dehydrogenase (Acadm) to display daily rhythms with peak values during daytime.” And that they decline as the day goes on. So to maximize beta oxidation, cardio should be done earlier in the day