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cancer cells are stupid so when it comes down to ketosis there are so many different directions that we can look at we’re not just looking at how you burn fat we’re not just looking at getting the best possible shape there’s actually some really good therapeutic applications and in this particular case I want to spend this video talking about the relationship between ketosis and cancer so with me I have Joe Anderson who is a PhD in chemical engineering and an expert in ketosis and you’ve done a lot of digging in the world of ketosis and cancer and I want to kind of turn the tables over to you to talk about what you’ve seen what you’ve discovered in that world and get a little discussion going on it sure so there’s there’s this idea out there that the ketosis can be therapeutic so if you can get to a certain level of therapy with your ketone levels they can actually decrease the cancer size I will say right up front there’s a gentleman down in southern Florida some of you may know Dom D’Agostino who’s actually actively doing research in this area so some of the stuff is coming from him but the idea is that cancer is tissue that’s growing out of control right and and cancer is made up of lots of cells so when it’s growing out of control some of those the fuel that’s fueling that out-of-control growth can be sugar so the idea is if you cut sugar out get into a high level of ketosis you’re gonna kill those cells right because they don’t have any nutrients to thrive on but you have to be careful because because every cell in that cancer isn’t necessarily being fuelled by sugar some will be fueled by fats so this doesn’t work for every cancer but they seem to indicate that some of the brain cancers the nasty ones are responsive to this keto therapy and then you have some other cancers as well the other idea within that is that some of the cancers are responding to the insulin so if you have sugar sugars driving your insulin to be elevated but that elevated insulin may also be helping the cancer grow out of control so once again decrease sugar decrease the fuel for the cancer cells but also decrease that insulin response that’s causing a response to those cancer cells as well gotcha now cancer is not my world expertise other than the fact I mean I lost my father to cancer in February so it’s near and dear to me but I still don’t have the breadth of knowledge that a lot of clinicians do and though in the world of cancer so can you just describe exactly how a cancer cell works and how it might feed and how it might be glycolytic just so that the viewers I’m an understanding of really how that works in general how keto could potentially starve that out sure and and I’m not going to try to pretend I’m a cancer expert but I’ve certainly done some research on this in terms of reading the scientific literature to understand it better but essentially cancer is a cell that doesn’t know when to stop growing and stop dividing so the cells your cell will grow grow grow and then at some point it can divide into a second cell but that process is well controlled in a cancer cell the control which is at this the DNA level is not properly there’s not a good stop to that so the cell will grow and divide and it’ll kind of pick up speed and it’ll continue to grow and divide grow and divide and that growth and division which is not controlled because the cell has had a mutation in the DNA or that that control isn’t present then the cancer grows out of control so the the cell needs fuel there’s two ways number one the fuel has to get there so you see a lot of blood vessel growth to get the sugars and the other nutrients to the the tumor the second thing is the fuel that’s typically going to use many times it will be sugar not necessarily all the time but the reason it uses sugar is because it’s simple you can use a simple pathway the mitochondria in the cells which is going to use fats and use other other other energy sources doesn’t have to be used when you’re burning sugar so so these the whole hypothesis is that these tumor cells are really growing after sugar as a fuel source and once again if you can cut back that sugar as a fuel source you can kill those cells and then potentially decrease the tumor size gotcha now when you talk about sort of the DNA of a cancer cell there’s been a lot of evidence it’s now starting to show that ketosis can alter gene expression and changing these in a positive way again this is maybe I put this is for you but looking at the fact that it can do that do you think that that’s one of the ways to is that maybe it’s gonna actually start corralling the the rogue cells of cancer cells that rogue portion of it by altering the gene expression even of the cancer cells so that’s certainly that’s certainly an interesting hypothesis and I well certainly I won’t be able to give you an answer of it but I think your point is the keto therapy is gonna be multifactorial meaning it’s gonna affect lots of different avenues it’s gonna cut off the sugar it may help Canoe it’s gonna help control the insulin it’s gonna change the DNA expression in some respects how powerful each one of those are will depend on not only the cancer but also how much in ketosis you’re at and and also other variables as well so they’re still trying to figure out that whole spectrum and I know some about it but there’s certainly other people who probably know that better than I do when I know dr. dawn D’Agostino at University of South Florida talks about in using ketosis actually as a catalyst to improve chemotherapy as well and then you might know some of his studies a little bit better than I do I know it’s sort of on the surface level and is that simply because it’s slowing down the growth so that the chemo can do its job or are there other reasons behind that it could be that at the other pieces you can imagine if you start to starve the cells the cells are very eager to take up more and more chemicals to continue their growth so if they’re eager to take up those chemicals when you put the kin with therapeutic right after the starvation phase that may make it more effective to kill the cells because they’re really point in as many chemicals as they can once again our hypothesis has not been demonstrated it has not been demonstrated but you’re right the fasting is what one thing he recommends before chemotherapy and also going a ketogenic diet both seem to have some beneficial effects and once again those studies are still being performed and we’re learning more about them as we speak now and that’s what I appreciate one of the things I appreciate most about dr. D’Agostino is how he he doesn’t say that ketosis is the end-all be-all he uses it as again I use this word a lot but uses as a catalyst for other things to work better and he’s not saying that everyone needs to be in ketosis and he’s not saying that you know it’s he’s not always predicating the the diet he’s moreso talking about here’s what’s happening here’s what’s happening in your body when you’re in ketosis and here’s why different things work better when you’re in state of ketosis and I think a lot of it simply has to do with inflammation which is something that I talk about a lot something that Dom talks about a lot and the fact that beta-hydroxybutyrate and these ketone bodies that we measure with devices like level are elevated when we’re in the state of ketosis and they in and of themselves or anti-inflammatory and inflammation has a direct correlation with cancer and it just creates a smoother transition a smoother communication between cells so that things can get done properly yeah and I just want to kind of piggyback and kind of say remember that even if you use keto therapeutics isn’t gonna be for every cancer and even if it does work on a cancer you got to be careful because there may be other regions in that cancer that actually use fat for fuel so it’s not going to be the end-all be-all but it certainly may help the therapies that you’re trying to provide to kill it yep I’m gonna leave with this noodle because this is an interesting thought and I want everyone to think about this too and you to think about it too because it just came to mind as a population as we get more keto adapted as we start utilizing more fats as a source of fuel do we potentially run the risk of cancers actually preferentially starting to run on fats more as it becomes the more prevalent fuel source now I’m not I’m just playing devil’s advocate here being totally honest and being an advocate for my viewers – by being playing devil’s advocate we don’t have to answer that right now but I want to I want to put some thought into that because as we become keto adapted to fat cells become key to adapt or do cancer cells become key to adapt to this well yeah it’s it’s simply unknown I my speculation is just all it is would be no I don’t think you may see some increase but I would imagine that the whole cancer rate would drop but that’s aspect I’m with I’m with you on that – I’m from the school thought that cancer cells are lazy and that’s why they want simple sugars they just want to grow they just they want to just consume they just want to consume and fat adaptation is to biochemically difficult for them to really I think it would take years and years it would take thousands and thousands if not tens of thousands of years for any kind of mutation like that to occur yeah we think about utilization of fats for fuels is more complex than your utilization of sugar for fuel that’s it I mean cancer cells are stupid so I’ll leave you with that cancer cells are stupid all right thanks Jeff yeah thank you
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Keto Diet vs. Cancer: Therapeutic Effects of a Low Carb Diet- Thomas DeLauer… Cancer cells are stupid, so – When it comes down to ketosis there are so many different directions that we can look.
We’re not just looking at how you burn fat. We’re not just looking at getting in the best possible shape. There are actually some really good therapeutic applications. In this particular case, I want to spend this video talking about the relationship between ketosis and cancer. So, with me I have Joe Anderson who is a PhD in chemical engineering and an expert in ketosis. You’ve done a lot of digging in the world of ketosis and cancer. I want to turn the tables over to you to talk about what you’ve seen, what you’ve discovered in that world, and get a little discussion going on. Sure. So, there’s this idea out there that the ketosis could be therapeutic. If you can get to a certain level of therapy with your ketone levels, it can actually decrease the cancer size. I will say right up front there’s a gentlemen down in southern Florida who some of you may know, Dom D’Agostino, whose actually actively doing research in this area. Some of this stuff is coming from him.
But, the idea is that cancer is tissue that’s growing out of control. Right? Cancer’s made up of lots of cells. When it’s growing out of control some of the fuel that’s fueling that out of control growth can be sugar. The idea is that if you cut sugar out, get into a high level of ketosis, you’re going to kill those cells because they don’t have any nutrients to thrive on. But, you have to be careful because every cell in that cancer isn’t necessarily being fueled by sugar. Some will be fueled by fats, so this doesn’t work for every cancer. They seem to indicate that some of the brain cancers, the nasty ones, are responsive to this keto therapy. Then you have some other cancers as well. .
The other idea within that is that some of the cancers are responding to the insulin so if you have sugar, sugar is driving your insulin to be elevated, but that elevated insulin may also be helping the cancer grow out of control. So, once again, decrease sugar, decrease the fuel for the cancer cells, but also decrease that insulin response that’s causing a response to those cancer cells as well. Right, now cancer is not my world of expertise other than the fact that I lost my father to cancer in February so it’s near and dear to me, but I still don’t have the breadth of knowledge that a lot of clinicians do in the world of cancer. Can you just describe exactly how a cancer cell works, and how it might feed, and how it might be glycolytic just so that the viewers who don’t have an understanding of really how that works in general and how keto could potentially starve that out?
Sure. I’m not going to try to pretend I’m’ a cancer expert, but I’ve certainly done some research on this in terms of reading the scientific literature to understand it better, but essentially cancer is a cell that doesn’t know when to stop growing and stop dividing. Your cell will grow, grow, grow and then at some point it can divide into a second cell, but that process is well controlled.