How Coffee Benefits Fasting & Keto Dieting | Keto Coffee | Coffee Benefits- Thomas DeLauer
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by now we know coffee is good we know Thomas likes coffee you know that Thomas wants you to drink coffee if you actually enjoy it we also probably know that Kido is pretty good we also probably know that fasting intermittent fasting is pretty good but why do they all work so well together and why does coffee actually enhance Kido and why does coffee enhance fasting it’s not just because the stuff tastes good or because we want to consume Kido Coffee no there’s actually a true physiological reason why consuming coffee is helping your Kido and fasting lifestyle out hey you are tuned into the internet’s leading performance nutrition keto and fasting channel new videos coming out every single Tuesday Friday and Sunday at 7 a.m. Pacific time and that’s not all we got a bunch of other videos including live broadcasts coming in throughout the course the week so make sure you hit that subscribe button also make sure you check out highly calm so you can see the latest and greatest performance apparel that I’m always wearing in my videos all right let’s get to some science so why coffee why is Thomas so obsessed with coffee well first of all it tastes good let’s talk about what it’s actually doing in your body so when it comes down to the keto and fasting world it’s all about the mobilization of fat and utilizing those fatty acids that are mobilizing in the proper way okay so first off of course caffeine and coffee has been known to already mobilize fat that means it allows fat to come out of the tissues and into the bloodstream that doesn’t necessarily constitute a burning effect though so let’s talk about how this works you see once fat is mobilized we require a few different things to happen specifically we require action by hormone sensitive lipase this is an enzyme that actually allows the fat loss and the fat burning to truly occur so what coffee and caffeine does is it inhibits something known as phosphodiester ease phosphodiesterases also known as PDE and the important thing to know about this phosphodiester ease is that it blocks the ability to normally burn fat you see if phosphodiesterases not inhibited if it’s not stopped it ends up in activating cyclic adenosine monophosphate also known as CA MP if CA MP is inactivated then we cannot activate hormone sensitive lipase I know that was complex so the simplest way to put it is that when you consume coffee you’re stopping the thing that stops fat-burning you’re basically disarming the guard okay you have this little guard known as phosphodiesterases that has different enzymes that is making it so you cannot burn fat you’re stopping the phosphodiester aids and you’re allowing the cmp to activate hormone sensitive lipase basically you mobilize the fat but now you’re enzymatically allowing your body to use that fat why is this good for keto because in keto you have so much fat being mobilized everything is telling the body to mobilize fat so if you can unlock the ability to burn that fat you’re in good shape same kind of idea with fasting fasting you’re mobilizing fat so while we’re talking about fasting let’s talk about something known as oto Fuji okay atif AG is simply put where your cells recycle where bigger more powerful cells consume weaker cells for fuel therefore survival the fittest you end up with a cleaner more effective body this is tremendous this is what we want out of fasting we get fat burning out of fasting but we also get this on top of G effect which makes us look and feel great it’s why your skin feels so renewed and fresh when you fast okay well believe it or not coffee has a tremendous effect on boosting autophagy even when you’re not fasting you see there’s a study that was published in the journal cell cycle that took a look at this it took a look at decaf or regular coffee okay and they had test subjects consumed either decaf or regular and they found that one to four hours after consuming again either decaf or regular they had a huge increase in their level of autopsy occurring predominantly in the liver in the heart this is really what they were measuring so yeah huge boost in autophagy occurring and they found that had to do with the polyphenols that were in the coffee not even necessarily the caffeine so where I find this interesting is that from a fasting or intermittent fasting perspective is worth getting an extra boost of otology we’re already in a cycle of auto feeding while we’re fasting but now we add coffee into the mix we’re getting even more okay even if it’s decaf then we add in the factor of the caffeine that mobilizes the fat wow we’re at like a triple whammy and we’re not even halfway through this video now the reason that coffee does this in terms of a fat burning effect on the effect is through the inhibition of what’s called mammalian target of rat myosin complex one mTOR 1c or m4 c1 okay basically what this mTOR c1 is is it’s an anabolic compound that’s released in the body but in the sake of auto fiji by definition we are at the opposite of anabolic we’re not building muscle even though we have some hormonal responses that are occurring that allow us to we’re actually in a breakdown phase but we want to be in this breakdown phase so by doing so it encourages cells to overall break down basically through what’s called the reduced phosphorylation of substrate p70 sk6 again all this means is that we’re allowing proteins to break down so so basically it’s a d acetylation process d acetylation is a complex way of saying breaking down so basically we’re allowing proteins to break on down so that cells can consume them and etapa G can occur again very complex way of just saying it boosts autofit G but for you science nerds out there I know you’re diggin it okay now let’s talk about coffee and actual ketone production for a second okay because what’s gonna happen is people are gonna come out and they’re gonna say that Thomas you’re talking about coffee mobilizing free fatty acids that doesn’t necessarily translate into ketone production so can you truly say that it helps ketosis well there’s a relatively recent study from 2016 that took a look at this and it’s a human study so it’s not on mice it’s very applicable it was published in the Canadian Journal of physiology and pharmacology took a look at ten subjects and these ten subjects they had go on a 12 hour fast at the end of a 12 hour fast they had them consume a simple breakfast with 85 grams of carbs nine and a half grams of fat and 14 grams of protein hardly a ketogenic diet right even had carbs and they were still wanted to measure what happened if they had coffee with that breakfast in terms of their overall ketone levels yes we can actually still produce ketones even when we’re not in a super nutritional state of ketosis so what they did is they had some of them consumed zero coffee some of them consumed one and a half cups of black coffee and some of them consumed three cups of black coffee well they found that the more coffee the more caffeine the more ketones that the were produced so they actually found of course those that consumes zero caffeine still had a little bit of ketones are being produced it’s kind of a natural process those that consumes one and a half cups of black coffee had 0.41 millimoles ketones getting in those that ended up consuming three cups of black coffee measured at 0.6 millimoles of ketones so yes nothing else changed everything was simple except for more caffeine and more caffeine yielded more ketones even when you weren’t officially in a nutritional state at ketosis you are basically in ketone emia where you had blood glucose and ketones present you weren’t a nutritional state of keto why did this happen well again it has to do again with that cyclic adenosine monophosphate that CA MP that I talked about the beginning of the video making a complex thing very simple it allowed ketogenesis to occur it encouraged fatty acids to get mobilized and get used by the liver and turned into fuel which leads me into again a lipolysis the mobilization so I know I touched on in the beginning but of course caffeine itself mobilizes more fats so we can encourage this to happen at an expedited rate we’ve got the polyphenols from the coffee that’s already encouraging Auto fangy and fat burning then we have the caffeine that’s flooding more fat to that process to begin with but as a result of this we actually have a temporary bout of insulin resistance whoa put on the brakes a second you just said you’re making the insulin resistant does that mean you’re making me diabetic no it means that temporarily your cells don’t want insulin this is actually a good thing when controlled basically they’ve become glucose refusing basically they refuse glucose and they refuse insulin because they’re feeling so good so think of it like this the body is doing so well that insulin comes along to deliver sugar deliver nutrients and the cells are like now I’m good I don’t need your help so they continue on thriving on their own this is what happens when you’re in a state of fasting and you also have some caffeine in the mix so a temporary insulin resistance helps us out it allows the cells to stay insulin sensitive so that later on they’ll be more receptive to what we consume what this means for those that are following a keto are fasting lifestyles it means that when you break your fast your cells are finally to want to consume and utilize what you took in this means that you’re going to be able to get your calories in you’ll be able to get your nutrients in during your eating window and you’re not going to fall victim to a micronutrient or macro nutrient deficiency for that matter so coffee is your friend and you can check out my other videos talking about coffee and caffeine and wintertime it and when to use it when not but for now at least this justifies that cup of joe that I’m about to have so as always keep it locked in to my videos comment below if you have any questions and I’ll answer them in the weekly Q&A video I’ll see you soon
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How Coffee Benefits Fasting & Keto Dieting… Thomas DeLauer discusses the positive effects of coffee on a keto diet or a fast.
In regards to fasting, coffee consumption helps promote autophagy and, as such, they’re a nice compliment of each other. A study published in the journal Cell Cycle looked to see the effects of both caffeinated and non-caffeinated coffee on autophagy. They found that both natural and decaffeinated brands of coffee similarly rapidly trigger autophagy in mice. One to four hours after coffee consumption, there was an increase in autophagy (autophagic flux) in all investigated organs (liver, muscle, heart).
These changes were accompanied by the inhibition of the enzymatic activity of mammalian target of rapamycin complex 1 (mTORC1), leading to the reduced phosphorylation of p70S6. Researchers looked to find the underlying mechanisms and found that both acute and chronic administration of coffee did reduce the phosphorylation of the mTORC1 substrate p70S6K, suggesting that this nutrient sensor is the reason for pro-autophagic signaling. Due to both caffeinated and non-caffeinated versions inducing autophagy researchers concluded that the polyphenols contained in coffee promote health by stimulating autophagy.
Coffee contains multiple polyphenols, and a range of chemically different phenolic compounds have been demonstrated capable to stimulate the deacetylation of cellular proteins, which induces autophagic activity. Specifically, “autophagy induction by coffee is linked to the deacetylation of cellular proteins as well as to the inhibition of mTORC1.” In the study, entitled Caffeine intake increases plasma ketones: an acute metabolic study in humans, Canadian researchers evaluated the effects of caffeine consumption in a group of 10 volunteers. They fasted for 12 hours and then ate a breakfast that consisted of 85g carbs, 9.5g fats, 14g protein. These individuals were then given either no caffeine, the equivalent of about a cup and a half of coffee, or a caffeine equivalent of 3 cups of coffee. Blood samples were then taken to evaluate not only the caffeine levels over a four hour period of time, but also the levels of ketones that were manufactured in the liver from the liberation of body fat. Higher doses of caffeine in the 10 healthy adults dramatically increased bHB, one of the most studied ketones as it relates to powering the brain.
Levels of bHB after 4 hours:
No caffeine = roughly 300 u mol/L = 0.3 mmol
2.5 mg/kg = roughly 410 u mol/L = 0.41 mmol
5.0 mg/kg = 600 u mol/L = 0.6 mmol
The increase in free fatty acids as well as β-hydroxybuterate is explained by caffeine blocking phosphodiesterase (PDE), preventing the inactivation of cyclic adenosine monophosphate (cAMP) – with increased caffeine leading to higher levels of cAMP.
Cyclic adenosine monophosphate (cAMP) is a cellular messenger that is involved with transferring hormones such as glucagon, which is the main catabolic hormone of the body and which functions to raise both the concentration of glucose and fat in the bloodstream and has the opposite effect of insulin). Therefore, caffeine has a “negative” effect on insulin sensitivity, but not on insulin itself
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